Magnetic Resonance Imaging of Differential Compartmental

نویسندگان

  • Joseph L. Demer
  • Robert A. Clark
چکیده

20 Activity in horizontal rectus extraocular muscles (EOMs) was investigated by magnetic 21 resonance imaging (MRI) of humans during asymmetrical convergence to a monocularly aligned 22 target at 15 cm distance, or monocular fixation of afocal targets placed over a wide range of 23 conjugate abduction through adduction. Cross sections and posterior partial volumes (PPV) of 24 EOMs were determined from quasi-coronal image planes, and were separately analyzed in the 25 inferior vs. superior compartments, defined by lines bisecting their maximum vertical 26 dimensions. Both inferior and superior compartments of medial (MR) and lateral rectus (LR) 27 exhibited contractile changes in PPV and maximum cross section for both asymmetric 28 convergence and a comparable range of conjugate adduction. Both LR compartments, and the 29 inferior MR compartment, exhibited similar decreases in contractility correlating with relaxation 30 during both convergence and conjugate adduction. In contrast, the superior MR compartment 31 exhibited roughly three times the contractility in conjugate adduction as in similar magnitude 32 convergence. In the aligned eye that did not move during convergence, summed contractility in 33 all compartments of MR and LR exhibited co-relaxation consistent with published EOM force 34 measurements in this paradigm (Miller et al. 2002; Miller et al. 2011). The superior MR 35 compartment also exhibited significantly greater contractility than the other compartments over 36 the maximum achievable horizontal globe rotation from abduction to adduction. These findings 37 suggest that the superior MR compartment is controlled differentially from the inferior 38 compartment, and suggest that its activity is reduced during convergence as a component of 39 generally altered extraocular mechanics. 40

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تاریخ انتشار 2014